Do not pre-clean ear prior to or during use. Doing so will disrupt the enzyme system. Do not use in pets with known or suspected ear drum rupture or with known or suspected senstivity to corticosteroids such as pregnant or lactating females or exotics. Do not allow water in or near ear during use. If condition persists or worsens, consult a veterinarian. Consult veterinarian before administering in conjunction with other products. Keep out of reach of children. Not for use in humans. Store at room temperature.